Klinefelter syndrome (47, xxy) is a chromosomal variation in males in which one extra x chromosome is present, resulting in a xxy sex chromosome karyotype the extra x chromosome can affect physical, developmental, behavioral, and cognitive functioning common physical features may include tall stature, reduced. Klinefelter syndrome is a genetic disorder that doesn't have a cure, but most men who have it can live normal, healthy lives learn the causes, symptoms, and treatments. In 1942, klinefelter et al published a report on 9 men who had enlarged breasts, sparse facial and body hair, small testes, and an inability to produce sperm in 1959, these men with klinefelter syndrome were discovered to have an extra x chromosome (genotype xxy) instead of the usual male sex. Most often, klinefelter syndrome is the result of one extra x (written as xxy) occasionally, variations of the xxy chromosome count may occur, the most common being the xy/xxy mosaic in this variation, some of the cells in the male's body have an additional x chromosome, and the rest have the normal. Klinefelter syndrome (ks) is a condition that occurs in men who have an extra x chromosome read about the common symptoms and treatments. Klinefelter syndrome is often diagnosed at puberty, when the expected physical changes don't occur. Klinefelter syndrome is a genetic disorder that results when a male is born with an extra copy of the x chromosome learn about diagnosis and treatment. What is klinefelter syndrome klinefelter syndrome is a fairly common genetic condition found in males only many boys with klinefelter syndrome — also known as xxy syndrome — have no signs or symptoms, and some don't even know they have it until later in life the xxy condition that causes klinefelter syndrome.
Affecting males, symptoms can include small genitals and infertility it's estimated 1 in 500 men have klinefelter syndrome, but most are unaware. Klinefelter's syndrome is a genetic condition that only affects males the condition is present from birth and is due to an extra x chromosome. Klinefelter syndrome is the most common sex chromosome disorder affected males carry an additional x chromosome, which results in male hypogonadism, androgen deficiency, and impaired spermatogenesis some patients may exhibit all of the classic signs of this disorder, including gynecomastia,. Klinefelter syndrome (sometimes called klinefelter's, ks or xxy) is where boys and men are born with an extra x chromosome chromosomes are packages of genes found in every cell in the body two types of chromosome, called the sex chromosomes, determine the genetic sex of a baby these are named either x or y.
Klinefelter syndrome gets its name from a publication in 1942 by klinefelter, reifenstein, and albright describing a series of patients with gynecomastia, small testes, aspermatogenesis, androgen deficiency, and increased levels of follicle stimulating hormone of particular interest at that time was the association of primary. Klinefelter syndrome is a chromosomal condition that affects male physical and cognitive development its signs and symptoms vary among affected individuals affected individuals typically have small testes that do not produce as much testosterone as usual testosterone is the hormone that directs male sexual. When puberty starts and guys' bodies begin to make sex hormones, boys with klinefelter usually don't produce as much of the male hormone testosterone that doesn't make a guy less male, but it can affect things like penis and testicle growth, and growth of body hair and muscles boys with klinefelter syndrome may also.
Klinefelter syndrome (ks) also known as 47,xxy or xxy, is the set of symptoms that result from two or more x chromosomes in males the primary features are sterility and small testicles often, symptoms may be subtle and many people do not realize they are affected sometimes, symptoms are more prominent and may. Klinefelter syndrome (ks) is a common genetic condition affecting one in 450 men, but is only diagnosed in fewer than half of those affected | racgp. This is part of our series on hidden or stigmatised health conditions in men read the other articles in the series here klinefelter's syndrome is a genetic disorder that affects approximately one in 450 males each cell in the human body has 23 pairs of chromosomes the sex chromosomes in a female are.
Klinefelter's syndrome (ks) is due to the presence of one or more supernumerary x chromosomes aneuploidy 47,xxy is the most common abnormality of sex chromosomes in humans, with an incidence of 1/500 male live births only one- third of subjects with ks is, however, diagnosed the aim of this. Klinefelter syndrome occurs in approximately 120 per 1000 liveborn male births, based on pooled neonatal surveys however, diagnosis is not often made at birth, making the condition appear relatively rare clinically the phenotype of the prototypic 47,xxy case is well recognized: seminiferous tubule dysgenesis and.
Between 1 in 500 and 1 in 1000 males have klinefelter syndrome  variants of klinefelter syndrome occur more infrequently approximately 1 in 50,000 or fewer newborns has a variant of klinefelter syndrome most men are diagnosed as adults in the context of male infertility only 10% of males with. Originally identified by dr harry klinefelter in 1942, klinefelter's syndrome is a sex chromosome condition that most commonly produces the xxy genotype in males other karyotypes can be seen but are much less common such as the xxxy, causing even greater negative phenotypic effects it is associated with many.
Klinefelter syndrome, disorder of the human sex chromosomes that occurs in males klinefelter syndrome is one of the most frequent chromosomal disorders in males, occurring in approximately 1 in every 500 to 1,000 males it results from an unequal sharing of sex chromosomes very soon after fertilization. Klinefelter's syndrome is the most common genetic cause of human male infertility, but many cases remain undiagnosed because of substantial variation in clinical presentation and insufficient professional awareness of the syndrome itself early recognition and hormonal treatment of the disorder can substantially improve. What is klinefelter syndrome klinefelter syndrome is a genetic disorder affecting males that results from having an extra x chromosome subscribe - https:/. Learn about klinefelter syndrome, a genetic disorder that affects males.